The immunity system from mother's milk is the best armor for puppies to help them grow up with proper physical and cognitive development. Your puppies can be weaned from about 3-6 weeks of age. The emergence of his first tooth are the signal that the pup is ready for his first meal. So once breast feeding is over, continue healthy growth with Pedigree Puppy Weaning. It is mild and easy to digest for better absorption. Every kibble is rich in Calcium, Protein, essential Vitamins and Minerals for healthy growth. Pedigree® Puppy helps him grow strong and lets him enjoy all his puppy adventures.